Glucose area under the curve during oral glucose tolerance test as an index of glucose intolerance

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Assessing 1-h plasma glucose and shape of the glucose curve during oral glucose tolerance test.

OBJECTIVE To assess the cutoff values at different time points for impaired glucose regulation (IGR) and diabetes, the glucose curve and isolated 1-h hyperglycemia were monitored during an oral glucose tolerance test (OGTT). METHODS Two thousand eight hundred and eighty-six subjects (1300 men and 1586 women) were recruited to have an OGTT. Plasma was collected at 0, 30, 60, 120, and 180 min t...

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Assessing the shape of the glucose curve during an oral glucose tolerance test.

OBJECTIVE The oral glucose tolerance test (OGTT) is used to define the status of glucose tolerance based on the plasma glucose level at 120 min. The purpose of the present study was to identify parameters that determine the shape of the plasma glucose course measured at 0, 30, 60, 90, and 120 min during an OGTT. RESEARCH DESIGN AND METHODS OGTT data from 551 subjects (485 with normal glucose ...

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Prediction of Glucose Tolerance without an Oral Glucose Tolerance Test

Introduction Impaired glucose tolerance (IGT) is diagnosed by a standardized oral glucose tolerance test (OGTT). However, the OGTT is laborious, and when not performed, glucose tolerance cannot be determined from fasting samples retrospectively. We tested if glucose tolerance status is reasonably predictable from a combination of demographic, anthropometric, and laboratory data assessed at one ...

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Beyond the morphology of the glucose curve following an oral glucose tolerance test in obese youth.

BACKGROUND To describe the morphology of glucose curve during the oral glucose tolerance test (OGTT) and any association with glucose tolerance, insulin action and secretion in obese youth. STUDY DESIGN Cross-sectional. METHODS OGTT data of 553 patients were analysed. Subjects were divided in groups based on the morphology (i.e. monophasic, biphasic, triphasic and upward monotonous) of gluc...

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Oral glucose tolerance test‐based calculation identifies different glucose intolerance phenotypes within the impaired fasting glucose range

AIMS/INTRODUCTION The conventional oral glucose tolerance test (OGTT) cannot detect future diabetics among isolated impaired fasting glucose (is-IFG) nor normal glucose tolerant (NGT) groups. By analyzing the relationship between fasting (FPG) and 2-h plasma glucose (2hPG), the present study identifies is-IFG subjects liable to worsening glucose homeostasis. MATERIALS AND METHODS Oral glucose...

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ژورنال

عنوان ژورنال: Diabetology International

سال: 2015

ISSN: 2190-1678,2190-1686

DOI: 10.1007/s13340-015-0212-4